Novel genetic loci underlying human intracranial volume identified through genome-wide association
Identifieur interne : 000018 ( France/Analysis ); précédent : 000017; suivant : 000019Novel genetic loci underlying human intracranial volume identified through genome-wide association
Auteurs : Hieab H H. Adams [France] ; Derrek P. Hibar [France] ; Vincent Chouraki [France] ; Jason L. Stein [France] ; Paul A. Nyquist [France] ; Miguel E. Rentería [France] ; Stella Trompet [France] ; Alejandro Arias-Vasquez [Pays-Bas] ; Sudha Seshadri [États-Unis] ; Sylvane Desrivières [France] ; Ashley H. Beecham [États-Unis] ; Neda Jahanshad [France] ; Katharina Wittfeld [France] ; Sven Lee ; Lucija Abramovic [France] ; Saud Alhusaini [France] ; Najaf Amin [France] ; Micael Andersson ; Konstantinos Arfanakis [France] ; Benjamin S. Aribisala [France] ; Nicola J. Armstrong [Royaume-Uni] ; Lavinia Athanasiu [France] ; Tomas Axelsson [Suède] ; Alex Beiser [États-Unis] ; Bernard Bernard ; Joshua C. Bis [France] ; Laura Blanken ; Susan H. Blanton [Irlande (pays)] ; Mar Bohlken [France] ; Mar Boks [France] ; Janita Bralten [France] ; Adam M. Brickman [États-Unis] ; Owen Carmichael [États-Unis] ; M Mallar Chakravarty [Canada] ; Ganesh Chauhan [France] ; Qiang Chen [Portugal] ; Christophe Ching ; Gabriel Cuellar-Partida [France] ; Anouk Den Braber ; Nhat Trung Doan [Canada] ; Stefan Ehrlich [France] ; Irina Filippi ; Tian Ge [Royaume-Uni] ; Sudheer Giddaluru [France] ; Aaron L. Goldman ; Rebecca F. Gottesman [États-Unis] ; Corina U. Greven ; Oliver Grimm [Royaume-Uni] ; Michael E. Griswold ; Tulio Guadalupe [France] ; Johanna Hass [États-Unis] ; Unn K. Haukvik [France] ; Saima Hilal [France] ; Edith Ho [Hong Kong] ; David Ho ; Avram J. Ho [Allemagne] ; Mar Martin ; Deborah Janowitz [France] ; Tianye Jia [République populaire de Chine] ; Dalia Kasperaviciute [France] ; Sungeun Kim [France] ; Marieke Klein ; Bernd Kraemer [France] ; Phil H. Lee [États-Unis] ; Li Liao ; David C. Liewald [France] ; Lorna M. Lopez ; Michelle Luciano [États-Unis] ; Christine Macare [France] ; Mar Marquand ; Mar Matarin [Royaume-Uni] ; Karen A. Mather [France] ; Manuel Mattheisen [Danemark] ; Bernard Mazoyer [France] ; David Mckay [France] ; Rebekah Mcwhirter ; Yuri Milaneschi [France] ; Nazanin Mirza-Schreiber ; Ryan L. Muetzel [États-Unis] ; Susana Mu Oz Maniega ; Kwangsik Nho [France] ; Allison C. Nugent [Irlande (pays)] ; Loes M Olde Loohuis ; Jaap Oosterlaan ; Martina Martin ; Irene Pappa ; Lukas Pirpamer ; Sara Pudas ; Benno Pütz [Allemagne] ; Kumar B. Rajan [France] ; Adaikalavan Ramasamy [Royaume-Uni] ; Jennifer S. Richards ; Shannon L. Risacher [France] ; Robert Roiz-Santia Ez [France] ; Nanda Rommelse [Pays-Bas] ; Emma Rose [France] ; Natalie A. Royle [France] ; Tatjana Rundek ; Philipp G. S Mann [France] ; Claudia L. Satizabal [France] ; Li Schmaal [France] ; Andrew Schork [France] ; Li Shen [États-Unis] ; Jean Shin ; Elena Shumskaya ; Albert Smith ; Emma Sprooten [France] ; Lachlan T. Strike [France] ; Alex Teumer [Royaume-Uni] ; Russell Thomson ; Diana Tordesillas-Gutierrez ; Robert Toro [France] ; Daniah Trabzuni [France] ; Dhananjay Vaidya ; Jeroen Van Der Grond [France] ; Dennis Van Der Meer [Pays-Bas] ; Marjolein M J. Van Donkelaar [France] ; Kristel R. Van Eijk [Pays-Bas] ; Theo G M. Van Erp ; Daan Van Rooij [Pays-Bas] ; Esther Walton [France] ; Lars Westlye [France] ; Christophe Whelan [France] ; Beverly G. Windham [France] ; Anderson M. Winkler [Allemagne] ; Girma Woldehawariat [France] ; Christiane Wolf ; Thomas W. Wolfers ; Bing Xu ; Lisa R. Yanek [France] ; Jingyun Yang ; Alex Zijdenbos [France] ; Marcel Zwiers [France] ; Ingrid Agartz [Norvège] ; Neelum T. Aggarwal ; Laura Almasy [États-Unis] ; David A. Ames [Australie] ; Philippe Amouyel [France] ; Andreas Andreassen ; Sampath Arepalli [Pays-Bas] ; Amelia A. Assareh [Iran] ; Sandra Barral [France] ; Mark Bastin [Royaume-Uni] ; Diane M. Becker ; James T. Becker [États-Unis] ; David A. Bennett ; John B. Blangero [France] ; Hans Van Bokhoven [Pays-Bas] ; Dorret I. Boomsma [Royaume-Uni] ; Henry Brodaty [Australie] ; Rachel M. Brouwer [Pays-Bas] ; Han G. Brunner [Suisse] ; Randy L. Buckner ; Jan K. Buitelaar [Pays-Bas] ; Kazima B. Bulayeva [France] ; Wiepke Cahn [États-Unis] ; Vince D. Calhoun [France] ; Dara M. Cannon [États-Unis] ; Gianpiero L. Cavalleri [Irlande (pays)] ; Christophe Chen ; Ching-Yu Cheng ; Sven Cichon [Suisse] ; Mark Cookson [États-Unis] ; Aiden Corvin [Irlande (pays)] ; Benedicto Crespo-Facorro [France] ; Joanne E. Curran [Royaume-Uni] ; Michael Czisch [Pays-Bas] ; Anders M. Dale [États-Unis] ; Gareth E. Davies [Pays-Bas] ; Eco J C. De Geus [États-Unis] ; Philip L. De Jager [France] ; Greig I. De Zubicaray [Australie] ; Norman Delanty [France] ; Chantal Depondt [France] ; Anita L. Destefano [États-Unis] ; Allissa Dillman [France] ; Srdjan Djurovic ; Gary Donohoe [États-Unis] ; Wayne C. Drevets [États-Unis] ; Ravi Duggirala [France] ; Thomas Dyer [France] ; Susanne Erk [Allemagne] ; Thomas E. Espeseth [France] ; Denis A. Evans ; Iryna O. Fedko [France] ; Guillén Fernández ; Luigi Ferrucci ; Simon Fisher [Pays-Bas] ; Debra A. Fleischman [France] ; Ian Ford ; Tatiana M. Foroud [États-Unis] ; Peter Fox [France] ; Clyde Francks [France] ; Masaki Fukunaga [Japon] ; J Raphael Gibbs [États-Unis] ; David C. Glahn [France] ; Randy L. Gollub [États-Unis] ; Harald H H. Göring [Finlande] ; Hans J. Grabe [Allemagne] ; Robert Green [États-Unis] ; Oliver Gruber ; Vilmundur Gudnason [France] ; Sebastian Guelfi [France] ; Narelle K. Hansell [États-Unis] ; John Hardy [États-Unis] ; Catharina A. Hartman [États-Unis] ; Ryota Hashimoto [France] ; Katrin Hegenscheid [France] ; Andreas Heinz ; Stephanie Le Hellard [France] ; Dena G. Hernandez ; Dirk J. Heslenfeld [France] ; Beng-Choon Ho [France] ; Pieter J. Hoekstra [Pays-Bas] ; Wolfgang Hoffmann ; Albert Hofman [Pays-Bas] ; Florian Holsboer [Allemagne] ; Georg Homuth [Allemagne] ; Norbert Hosten [France] ; Jouke-Jan Hottenga [Royaume-Uni] ; Hilleke E Hulshoff Pol ; Masashi Ikeda [Japon] ; M Kamran Ikram [France] ; Clifford R Jack Jr ; Mark Jenkinson ; Robert Johnson [États-Unis] ; Erik G. Jönsson [Suède] ; J Wouter Jukema [France] ; René S. Kahn ; Ryota Kanai [France] ; Iwona Kloszewska [France] ; David S. Knopman [États-Unis] ; Peter Kochunov [France] ; John B. Kwok [Hong Kong] ; Stephen M. Lawrie [France] ; Hervé Lemaître [France] ; Xinmin Liu ; Dan L. Longo [France] ; W T Longstreth Jr ; Oscar L. Lopez [France] ; Simon Lovestone [Royaume-Uni] ; Oliver Martin ; Jean-Luc Martin ; Venkata S. Mattay [États-Unis] ; Colm Mcdonald [Royaume-Uni] ; Andrew Mcintosh [Australie] ; Katie L. Mcmahon [Australie] ; Francis J. Mcmahon ; Patrizia Mecocci [Italie] ; Ingrid Melle [Norvège] ; Andreas Meyer-Lindenberg [France] ; Sebastian Mohnke [France] ; Grant W. Montgomery [Australie] ; Derek W. Morris [France] ; Thomas H. Mosley [France] ; Thomas W. Mühleisen [Allemagne] ; Bertram Müller-Myhsok [Allemagne] ; Michael A. Nalls [France] ; Matthias Nauck [Allemagne] ; Thomas E. Nichols [Royaume-Uni] ; Wiro J. Niessen [Pays-Bas] ; Markus M. Nöthen [Allemagne] ; Lars Nyberg [Suède] ; Kazutaka Ohi [France] ; Rene L. Olvera [France] ; Roel A. Ophoff [Pays-Bas] ; Massimo Pandolfo [France] ; Tomas Paus [Canada] ; Zdenka Pausova [Canada] ; Brenda W J H. Penninx [Pays-Bas] ; G Bruce Pike ; Steven G. Potkin [France] ; Bruce M. Psaty [États-Unis] ; Simone Reppermund [Australie] ; Marcel Rietschel [Allemagne] ; Joshua L. Roffman [France] ; Nina Romanczuk-Seiferth [France] ; Jerome I. Rotter [États-Unis] ; Mina Ryten [France] ; Ralph L. Sacco ; Perminder S. Sachdev [Australie] ; Andrew Saykin [France] ; Reinhold Schmidt ; Peter R. Schofield [Australie] ; Sigurdur Sigurdsson [France] ; Andy Simmons ; Andrew Singleton [France] ; Sanjay M. Sisodiya [Royaume-Uni] ; Colin Smith ; Jordan W. Smoller [États-Unis] ; Hilkka Soininen [Finlande] ; Velandai Srikanth [France] ; Vidar M. Steen [France] ; David J. Stott [Royaume-Uni] ; Jessika E. Sussmann [France] ; Anbupalam Thalamuthu [France] ; Henning Tiemeier [Pays-Bas] ; Arthur W. Toga [États-Unis] ; Bryan J. Traynor [France] ; Juan Troncoso ; Jessica A. Turner [Royaume-Uni] ; Christophe Tzourio [France] ; Andre G. Uitterlinden [Pays-Bas] ; Maria C Valdés Hernández ; Marcel Van Der Brug [France] ; Aad Van Der Lugt [Pays-Bas] ; Nic J A. Van Der Wee [France] ; Cornelia M. Van Duijn [Pays-Bas] ; Neeltje E M. Van Haren [France] ; Dennis Van Ent ; Marie-Jose Van Tol [Pays-Bas] ; Badri N. Vardarajan ; Dick J. Veltman [France] ; Meike W. Vernooij [Pays-Bas] ; Henry Völzke [Allemagne] ; Henrik Walter [Allemagne] ; Joanna M. Wardlaw [Royaume-Uni] ; Thomas H. Wassink [États-Unis] ; Michael E. Weale [Royaume-Uni] ; Wei Weinberger ; Wei Weiner ; Wei Wen [Hong Kong] ; Eric Westman [France] ; Tonya White [Royaume-Uni] ; Tien Y. Wong [France] ; Clinton B. Wright [États-Unis] ; H Ronald Zielke ; Alan B. Zonderman [France] ; Ian J. Deary [France] ; Charles Decarli [France] ; Helena Schmidt [Pays-Bas] ; Nicholas G. Martin ; Anton J M. De Craen [Pays-Bas] ; Margaret J. Wright [États-Unis] ; Lenore J. Launer ; Gunter Schumann [Allemagne] ; Myriam Fornage [France] ; Barbara Franke [Pays-Bas] ; Stéphanie Debette [France] ; Sarah E. Medland [France] ; M Arfan Ikram [France] ; Paul M. Thompson [États-Unis]Source :
- Nature Neuroscience [ 1097-6256 ] ; 2016.
English descriptors
Abstract
Intracranial volume reflects the maximally attained brain size during development, and remains stable with loss of tissue in late life. It is highly heritable, but the underlying genes remain largely undetermined. In a genome-wide association study of 32,438 adults, we discovered five previously unknown loci for intracranial volume and confirmed two known signals. Four of the loci were also associated with adult human stature, but these remained associated with intracranial volume after adjusting for height. We found a high genetic correlation with child head circumference (ρgenetic = 0.748), which indicates a similar genetic background and allowed us to identify four additional loci through meta-analysis (Ncombined = 37,345). Variants for intracranial volume were also related to childhood and adult cognitive function, and Parkinson's disease, and were enriched near genes involved in growth pathways, including PI3K-AKT signaling. These findings identify the biological underpinnings of intracranial volume and their link to physiological and pathological traits.
Url:
DOI: 10.1038/nn.4398
Affiliations:
- Allemagne, Australie, Canada, Danemark, Finlande, France, Hong Kong, Iran, Irlande (pays), Italie, Japon, Norvège, Pays-Bas, Portugal, Royaume-Uni, République populaire de Chine, Suisse, Suède, États-Unis
- Alsace (région administrative), Aquitaine, Basse-Saxe, East Middle Sweden, Grand Est, Lorraine (région), Nouvelle-Aquitaine, Pennsylvanie, Québec, Svealand, Écosse
- Bordeaux, Glasgow, Göttingen, Metz, Montréal, Nancy, Pittsburgh, Strasbourg, Uppsala
- Université McGill, Université Strasbourg 1, Université d'Uppsala, Université de Bordeaux, Université de Glasgow, Université de Göttingen, Université de Lorraine, Université de Pittsburgh, Université de Strasbourg
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Hal:hal-01382716Le document en format XML
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China</addrLine> <country key="CN"></country> </address> <ref type="url">http://english.bnu.edu.cn/</ref> </desc></hal:affiliation><country>République populaire de Chine</country></affiliation></author><author><name sortKey="Kasperaviciute, Dalia" sort="Kasperaviciute, Dalia" uniqKey="Kasperaviciute D" first="Dalia" last="Kasperaviciute">Dalia Kasperaviciute</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-431804" status="INCOMING"> <orgName>Department of Medicine, Imperial College London, London W12 0NN, UK</orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Kim, Sungeun" sort="Kim, Sungeun" uniqKey="Kim S" first="Sungeun" last="Kim">Sungeun Kim</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-162285" status="VALID"> <idno type="IdRef">166895385</idno> <idno type="RNSR">199712611A</idno> <idno type="IdUnivLorraine">[UL]RPH--</idno> <orgName>Structure et Réactivité des Systèmes Moléculaires Complexes</orgName> <orgName type="acronym">SRSMC</orgName> <date type="start">2012-01-01</date> <desc> <address> <addrLine>Université de Lorraine, Faculté des Sciences et Techniques, BP 70239, 54506 Vandoeuvre les Nancy Cedex</addrLine> <country key="FR"></country> </address> <ref type="url">http://www.srsmc.univ-lorraine.fr/</ref> </desc> <listRelation> <relation active="#struct-413289" type="direct"></relation> <relation name="UMR7565" active="#struct-441569" type="direct"></relation> </listRelation><tutelles><tutelle active="#struct-413289" type="direct"><org type="institution" xml:id="struct-413289" status="VALID"> <idno type="IdRef">157040569</idno> <idno type="IdUnivLorraine">[UL]100--</idno> <orgName>Université de Lorraine</orgName> <orgName type="acronym">UL</orgName> <date type="start">2012-01-01</date> <desc> <address> <addrLine>34 cours Léopold - CS 25233 - 54052 Nancy cedex</addrLine> <country key="FR"></country> </address> <ref type="url">http://www.univ-lorraine.fr/</ref> </desc></org></tutelle><tutelle name="UMR7565" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"> <idno type="IdRef">02636817X</idno> <idno type="ISNI">0000000122597504</idno> <orgName>Centre National de la Recherche Scientifique</orgName> <orgName type="acronym">CNRS</orgName> <date type="start">1939-10-19</date> <desc> <address> <country key="FR"></country> </address> <ref type="url">http://www.cnrs.fr/</ref> </desc></org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Nancy</settlement><settlement type="city">Metz</settlement><region type="region" nuts="2">Grand Est</region><region type="old region" nuts="2">Lorraine (région)</region></placeName><orgName type="university">Université de Lorraine</orgName></affiliation></author><author><name sortKey="Klein, Marieke" sort="Klein, Marieke" uniqKey="Klein M" first="Marieke" last="Klein">Marieke Klein</name></author><author><name sortKey="Kraemer, Bernd" sort="Kraemer, Bernd" uniqKey="Kraemer B" first="Bernd" last="Kraemer">Bernd Kraemer</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-431785" status="INCOMING"> <orgName>Center for Translational Research in Systems Neuroscience and Psychiatry, Department of Psychiatry and Psychotherapy, University Medical Center, Goettingen 37075, Germany </orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Lee, Phil H" sort="Lee, Phil H" uniqKey="Lee P" first="Phil H" last="Lee">Phil H. 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Box 9101 6500 HB Nijmegen </addrLine> <country key="NL"></country> </address> <ref type="url">https://www.radboudumc.nl/EN</ref> </desc></org></tutelle></tutelles></hal:affiliation><country>Pays-Bas</country></affiliation></author><author><name sortKey="Boomsma, Dorret I" sort="Boomsma, Dorret I" uniqKey="Boomsma D" first="Dorret I" last="Boomsma">Dorret I. 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Dale</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-468732" status="INCOMING"> <orgName>Departments of Neurosciences, Radiology, Psychiatry, and Cognitive Science, University of California, San Diego, La Jolla, CA 92093-0841, USA</orgName> <desc> <address> <country key="US"></country> </address> </desc></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Davies, Gareth E" sort="Davies, Gareth E" uniqKey="Davies G" first="Gareth E" last="Davies">Gareth E. 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Roffman</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-431781" status="INCOMING"> <orgName>Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02115, USA </orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Romanczuk Seiferth, Nina" sort="Romanczuk Seiferth, Nina" uniqKey="Romanczuk Seiferth N" first="Nina" last="Romanczuk-Seiferth">Nina Romanczuk-Seiferth</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-431828" status="INCOMING"> <orgName>Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, CCM, Berlin 10117, Germany </orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Rotter, Jerome I" sort="Rotter, Jerome I" uniqKey="Rotter J" first="Jerome I" last="Rotter">Jerome I. Rotter</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-420226" status="INCOMING"> <orgName>Medical Genetics Institute, Cedars-Sinai Medical Center</orgName> <desc> <address> <addrLine>Los Angeles, CA;</addrLine> <country key="US"></country> </address> </desc></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Ryten, Mina" sort="Ryten, Mina" uniqKey="Ryten M" first="Mina" last="Ryten">Mina Ryten</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-431854" status="INCOMING"> <orgName>Department of Medical and Molecular Genetics, King’s College London, London SE1 9RT, UK </orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Sacco, Ralph L" sort="Sacco, Ralph L" uniqKey="Sacco R" first="Ralph L" last="Sacco">Ralph L. Sacco</name><affiliation><hal:affiliation type="institution" xml:id="struct-468987" status="INCOMING"> <orgName>Metacohorts Consortium</orgName></hal:affiliation></affiliation></author><author><name sortKey="Sachdev, Perminder S" sort="Sachdev, Perminder S" uniqKey="Sachdev P" first="Perminder S" last="Sachdev">Perminder S. 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Steen</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-431775" status="INCOMING"> <orgName>NORMENT - KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, 5021 Bergen, Norway </orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Stott, David J" sort="Stott, David J" uniqKey="Stott D" first="David J" last="Stott">David J. 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Box 9600, Albinusdreef 2, 2300 RC Leiden</addrLine> <country key="NL"></country> </address> </desc> <listRelation> <relation active="#struct-329273" type="direct"></relation> </listRelation><tutelles><tutelle active="#struct-329273" type="direct"><org type="institution" xml:id="struct-329273" status="INCOMING"> <orgName>Leiden University Medical Center</orgName> <desc> <address> <country key="FR"></country> </address> </desc></org></tutelle></tutelles></hal:affiliation><country>Pays-Bas</country></affiliation></author><author><name sortKey="Wright, Margaret J" sort="Wright, Margaret J" uniqKey="Wright M" first="Margaret J" last="Wright">Margaret J. 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Medland</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-420528" status="INCOMING"> <orgName>Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia</orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Ikram, M Arfan" sort="Ikram, M Arfan" uniqKey="Ikram M" first="M Arfan" last="Ikram">M Arfan Ikram</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-420494" status="INCOMING"> <orgName>Department of Radiology, Erasmus Medical Center University Medical Center, Rotterdam, The Netherlands</orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Thompson, Paul M" sort="Thompson, Paul M" uniqKey="Thompson P" first="Paul M" last="Thompson">Paul M. Thompson</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-464414" status="INCOMING"> <orgName>Imaging Genetics Center, Mark & Mary Stevens Neuroimaging & Informatics Institute, University of Southern California, Marina del Rey, CA, USA</orgName> <desc> <address> <country key="US"></country> </address> </desc></hal:affiliation><country>États-Unis</country></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">HAL</idno><idno type="RBID">Hal:hal-01382716</idno><idno type="halId">hal-01382716</idno><idno type="halUri">https://hal.archives-ouvertes.fr/hal-01382716</idno><idno type="url">https://hal.archives-ouvertes.fr/hal-01382716</idno><idno type="doi">10.1038/nn.4398</idno><date when="2016">2016</date><idno type="wicri:Area/Hal/Corpus">000003</idno><idno type="wicri:Area/Hal/Curation">000003</idno><idno type="wicri:Area/Hal/Checkpoint">000001</idno><idno type="wicri:explorRef" wicri:stream="Hal" wicri:step="Checkpoint">000001</idno><idno type="wicri:doubleKey">1097-6256:2016:Adams H:novel:genetic:loci</idno><idno type="wicri:Area/Main/Merge">000136</idno><idno type="wicri:Area/Main/Curation">000136</idno><idno type="wicri:Area/Main/Exploration">000136</idno><idno type="wicri:Area/France/Extraction">000018</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Novel genetic loci underlying human intracranial volume identified through genome-wide association</title><author><name sortKey="Adams, Hieab H H" sort="Adams, Hieab H H" uniqKey="Adams H" first="Hieab H H" last="Adams">Hieab H H. Adams</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-21646" status="OLD"> <orgName>Institut Gilbert-Laustriat : Biomolécules, Biotechnologie, Innovation Thérapeutique</orgName> <desc> <address> <addrLine>Boulevard Sébastien Brandt BP 10413 67412 ILLKIRCH CEDEX</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation active="#struct-300320" type="direct"></relation> <relation name="UMR7175" active="#struct-441569" type="direct"></relation> </listRelation><tutelles><tutelle active="#struct-300320" type="direct"><org type="institution" xml:id="struct-300320" status="VALID"> <orgName>Université Louis Pasteur - Strasbourg I</orgName> <desc> <address> <country key="FR"></country> </address> </desc></org></tutelle><tutelle name="UMR7175" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"> <idno type="IdRef">02636817X</idno> <idno type="ISNI">0000000122597504</idno> <orgName>Centre National de la Recherche Scientifique</orgName> <orgName type="acronym">CNRS</orgName> <date type="start">1939-10-19</date> <desc> <address> <country key="FR"></country> </address> <ref type="url">http://www.cnrs.fr/</ref> </desc></org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Strasbourg</settlement><region type="region" nuts="2">Grand Est</region><region type="old region" nuts="2">Alsace (région administrative)</region></placeName><orgName type="university">Université Strasbourg 1</orgName><orgName type="institution" wicri:auto="newGroup">Université de Strasbourg</orgName></affiliation></author><author><name sortKey="Hibar, Derrek P" sort="Hibar, Derrek P" uniqKey="Hibar D" first="Derrek P" last="Hibar">Derrek P. Hibar</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-420527" status="INCOMING"> <orgName>Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California, Los Angeles, California, USA</orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Chouraki, Vincent" sort="Chouraki, Vincent" uniqKey="Chouraki V" first="Vincent" last="Chouraki">Vincent Chouraki</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-164505" status="VALID"> <orgName>Université Lille Nord de France</orgName> <desc> <address> <addrLine>COMUE Lille Nord de France - 365 bis, rue Jules Guesde BP 50458 - 59658 Villeneuve d’Ascq Cedex Université Lille Nord de France CS 90005 -F- 59044 Lille cedex </addrLine> <country key="FR"></country> </address> <ref type="url">http://www.cue-lillenorddefrance.fr/</ref> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Stein, Jason L" sort="Stein, Jason L" uniqKey="Stein J" first="Jason L" last="Stein">Jason L. Stein</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-420527" status="INCOMING"> <orgName>Laboratory of Neuro Imaging, David Geffen School of Medicine, University of California, Los Angeles, California, USA</orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Nyquist, Paul A" sort="Nyquist, Paul A" uniqKey="Nyquist P" first="Paul A" last="Nyquist">Paul A. 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Box 9101 6500 HB Nijmegen </addrLine> <country key="NL"></country> </address> <ref type="url">https://www.radboudumc.nl/EN</ref> </desc></org></tutelle></tutelles></hal:affiliation><country>Pays-Bas</country></affiliation></author><author><name sortKey="Seshadri, Sudha" sort="Seshadri, Sudha" uniqKey="Seshadri S" first="Sudha" last="Seshadri">Sudha Seshadri</name><affiliation wicri:level="1"><hal:affiliation type="department" xml:id="struct-457651" status="INCOMING"> <orgName>Department of Neurology [Boston, USA]</orgName> <desc> <address> <addrLine>72 E Concord St, Boston, MA 02118</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-457650" type="direct"></relation> </listRelation><tutelles><tutelle active="#struct-457650" type="direct"><org type="institution" xml:id="struct-457650" status="INCOMING"> <orgName>Boston University School of Medicine [Boston, USA]</orgName> <desc> <address> <addrLine>72 E Concord St, Boston, MA 02118</addrLine> <country key="US"></country> </address> </desc></org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Desrivieres, Sylvane" sort="Desrivieres, Sylvane" uniqKey="Desrivieres S" first="Sylvane" last="Desrivières">Sylvane Desrivières</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-431762" status="INCOMING"> <orgName>MRC- SGDP Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London SE5 8AF, UK </orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Beecham, Ashley H" sort="Beecham, Ashley H" uniqKey="Beecham A" first="Ashley H" last="Beecham">Ashley H. 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Bis</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-420488" status="INCOMING"> <orgName>Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA</orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Blanken, Laura" sort="Blanken, Laura" uniqKey="Blanken L" first="Laura" last="Blanken">Laura Blanken</name></author><author><name sortKey="Blanton, Susan H" sort="Blanton, Susan H" uniqKey="Blanton S" first="Susan H" last="Blanton">Susan H. 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S Mann</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-431793" status="INCOMING"> <orgName>Max Planck Institute of Psychiatry, Munich 80804, Germany </orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Satizabal, Claudia L" sort="Satizabal, Claudia L" uniqKey="Satizabal C" first="Claudia L" last="Satizabal">Claudia L. 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O. Box 4950 Nydalen - N-0424 Oslo</addrLine> <country key="NO"></country> </address> </desc> <listRelation> <relation active="#struct-50791" type="direct"></relation> <relation active="#struct-333179" type="direct"></relation> <relation active="#struct-453931" type="direct"></relation> </listRelation><tutelles><tutelle active="#struct-50791" type="direct"><org type="institution" xml:id="struct-50791" status="VALID"> <orgName>University of Oslo</orgName> <orgName type="acronym">UiO</orgName> <desc> <address> <addrLine>P.O 1072 Blindern 0316 Oslo</addrLine> <country key="NO"></country> </address> <ref type="url">http://www.uio.no/english/</ref> </desc></org></tutelle><tutelle active="#struct-333179" type="direct"><org type="institution" xml:id="struct-333179" status="INCOMING"> <orgName>Institute of Clinical Medicine</orgName> <desc> <address> <country key="FR"></country> </address> </desc></org></tutelle><tutelle active="#struct-453931" type="direct"><org type="institution" xml:id="struct-453931" status="INCOMING"> <orgName>Oslo University Hospital</orgName> <desc> <address> <country key="NO"></country> </address> </desc></org></tutelle></tutelles></hal:affiliation><country>Norvège</country></affiliation></author><author><name sortKey="Aggarwal, Neelum T" sort="Aggarwal, Neelum T" uniqKey="Aggarwal N" first="Neelum T" last="Aggarwal">Neelum T. 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Foroud</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-172459" status="INCOMING"> <orgName>Department of Medical and Molecular Genetics</orgName> <desc> <address> <addrLine>Indianapolis, Indiana</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-321989" type="direct"></relation> </listRelation><tutelles><tutelle active="#struct-321989" type="direct"><org type="institution" xml:id="struct-321989" status="INCOMING"> <orgName>Indiana University School of Medicine</orgName> <desc> <address> <country key="FR"></country> </address> </desc></org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Fox, Peter" sort="Fox, Peter" uniqKey="Fox P" first="Peter" last="Fox">Peter Fox</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-431814" status="INCOMING"> <orgName>University of Texas Health Science Center, San Antonio, Texas 78229, USA</orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Francks, Clyde" sort="Francks, Clyde" uniqKey="Francks C" first="Clyde" last="Francks">Clyde Francks</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-431777" status="INCOMING"> <orgName>Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen 6525 XD, The Netherlands </orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Fukunaga, Masaki" sort="Fukunaga, Masaki" uniqKey="Fukunaga M" first="Masaki" last="Fukunaga">Masaki Fukunaga</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-264860" status="INCOMING"> <orgName>Department of Physics, Okayama University</orgName> <desc> <address> <addrLine>Okayama 700-8530</addrLine> <country key="JP"></country> </address> </desc> <listRelation> <relation active="#struct-304334" type="direct"></relation> </listRelation><tutelles><tutelle active="#struct-304334" type="direct"><org type="institution" xml:id="struct-304334" status="INCOMING"> <orgName>Department of Physics</orgName> <desc> <address> <country key="FR"></country> </address> </desc></org></tutelle></tutelles></hal:affiliation><country>Japon</country></affiliation></author><author><name sortKey="Gibbs, J Raphael" sort="Gibbs, J Raphael" uniqKey="Gibbs J" first="J Raphael" last="Gibbs">J Raphael Gibbs</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-453277" status="INCOMING"> <orgName>Laboratory of Neurogenetics</orgName> <desc> <address> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-323617" type="direct"></relation> </listRelation><tutelles><tutelle active="#struct-323617" type="direct"><org type="institution" xml:id="struct-323617" status="INCOMING"> <orgName>National Institute of Aging</orgName> <desc> <address> <country key="FR"></country> </address> </desc></org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Glahn, David C" sort="Glahn, David C" uniqKey="Glahn D" first="David C" last="Glahn">David C. 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Martinos Center for Biomedical Imaging</orgName> <desc> <address> <addrLine>149 Thirteenth Street, Suite 2301 Charlestown, Massachusetts 02129</addrLine> <country key="US"></country> </address> <ref type="url">http://www.nmr.mgh.harvard.edu/martinos</ref> </desc> <listRelation> <relation active="#struct-309442" type="direct"></relation> <relation active="#struct-372514" type="direct"></relation> </listRelation><tutelles><tutelle active="#struct-309442" type="direct"><org type="institution" xml:id="struct-309442" status="VALID"> <orgName>Massachusetts General Hospital [Boston]</orgName> <desc> <address> <addrLine>55 Fruit StreetBoston, MA 02114</addrLine> <country key="US"></country> </address> <ref type="url">http://www.massgeneral.org/</ref> </desc></org></tutelle><tutelle active="#struct-372514" type="direct"><org type="institution" xml:id="struct-372514" status="INCOMING"> <orgName>Harvard Medical School</orgName> <desc> <address> <country key="FR"></country> </address> </desc></org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Goring, Harald H H" sort="Goring, Harald H H" uniqKey="Goring H" first="Harald H H" last="Göring">Harald H H. 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Grabe</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-268175" status="INCOMING"> <orgName>Department of Psychiatry and Psychotherapy</orgName> <desc> <address> <addrLine>Rostocker Chaussee 70- 18435 Stralsund</addrLine> <country key="DE"></country> </address> </desc> <listRelation> <relation active="#struct-380134" type="direct"></relation> <relation active="#struct-380135" type="direct"></relation> </listRelation><tutelles><tutelle active="#struct-380134" type="direct"><org type="institution" xml:id="struct-380134" status="INCOMING"> <orgName>University Medicine Greifswald,</orgName> <desc> <address> <country key="FR"></country> </address> </desc></org></tutelle><tutelle active="#struct-380135" type="direct"><org type="institution" xml:id="struct-380135" status="INCOMING"> <orgName>HELIOS Hospital Stralsund</orgName> <desc> <address> <country key="FR"></country> </address> </desc></org></tutelle></tutelles></hal:affiliation><country>Allemagne</country></affiliation></author><author><name sortKey="Green, Robert" sort="Green, Robert" uniqKey="Green R" first="Robert" last="Green">Robert Green</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-97027" status="VALID"> <orgName>Department of Mathematics, University of Colorado</orgName> <desc> <address> <addrLine>Campus Box 395, Boulder CO 80309-0395, U. S. A.</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-302215" type="direct"></relation> </listRelation><tutelles><tutelle active="#struct-302215" type="direct"><org type="institution" xml:id="struct-302215" status="VALID"> <orgName>University of Colorado Boulder [Boulder]</orgName> <desc> <address> <addrLine>Boulder, Colorado 80309</addrLine> <country key="US"></country> </address> <ref type="url">http://www.colorado.edu/</ref> </desc></org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Gruber, Oliver" sort="Gruber, Oliver" uniqKey="Gruber O" first="Oliver" last="Gruber">Oliver Gruber</name></author><author><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-420491" status="INCOMING"> <orgName>Icelandic Heart Association, Kopavogur, Iceland. </orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Guelfi, Sebastian" sort="Guelfi, Sebastian" uniqKey="Guelfi S" first="Sebastian" last="Guelfi">Sebastian Guelfi</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-431809" status="INCOMING"> <orgName>Reta Lila Weston Institute and Department of Molecular Neuroscience, UCL Institute of Neurology, London WC1N 3BG, UK </orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Hansell, Narelle K" sort="Hansell, Narelle K" uniqKey="Hansell N" first="Narelle K" last="Hansell">Narelle K. 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Mosley</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-420547" status="INCOMING"> <orgName>Department of Medicine (Geriatrics), University of Mississippi Medical Center, Jackson, Mississippi, USA</orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Muhleisen, Thomas W" sort="Muhleisen, Thomas W" uniqKey="Muhleisen T" first="Thomas W" last="Mühleisen">Thomas W. 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Niessen</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-338687" status="VALID"> <orgName>Erasmus University Medical Centre Rotterdam [Rotterdam]</orgName> <desc> <address> <addrLine>s-Gravendijkwal 230, 3015 CE Rotterdam</addrLine> <country key="NL"></country> </address> </desc></hal:affiliation><country>Pays-Bas</country></affiliation></author><author><name sortKey="Nothen, Markus M" sort="Nothen, Markus M" uniqKey="Nothen M" first="Markus M" last="Nöthen">Markus M. 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Montréal (Québec) Canada H3A 0G4</addrLine> <country key="CA"></country> </address> <ref type="url">http://www.mcgill.ca/</ref> </desc></org></tutelle><tutelle active="#struct-305938" type="direct"><org type="institution" xml:id="struct-305938" status="INCOMING"> <orgName>Montreal Neurological Institute</orgName> <desc> <address> <country key="FR"></country> </address> </desc></org></tutelle></tutelles></hal:affiliation><country>Canada</country><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName><orgName type="university">Université McGill</orgName></affiliation></author><author><name sortKey="Pausova, Zdenka" sort="Pausova, Zdenka" uniqKey="Pausova Z" first="Zdenka" last="Pausova">Zdenka Pausova</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-468721" status="INCOMING"> <orgName>Departments of Physiology and Nutritional Sciences, University of Toronto, Toronto, Canada</orgName> <desc> <address> <country key="CA"></country> </address> </desc></hal:affiliation><country>Canada</country></affiliation></author><author><name sortKey="Penninx, Brenda W J H" sort="Penninx, Brenda W J H" uniqKey="Penninx B" first="Brenda W J H" last="Penninx">Brenda W J H. 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Potkin</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-431834" status="INCOMING"> <orgName>Psychiatry and Human Behavior, University of California, Irvine, California 92617, USA </orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Psaty, Bruce M" sort="Psaty, Bruce M" uniqKey="Psaty B" first="Bruce M" last="Psaty">Bruce M. 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Roffman</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-431781" status="INCOMING"> <orgName>Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02115, USA </orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Romanczuk Seiferth, Nina" sort="Romanczuk Seiferth, Nina" uniqKey="Romanczuk Seiferth N" first="Nina" last="Romanczuk-Seiferth">Nina Romanczuk-Seiferth</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-431828" status="INCOMING"> <orgName>Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, CCM, Berlin 10117, Germany </orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Rotter, Jerome I" sort="Rotter, Jerome I" uniqKey="Rotter J" first="Jerome I" last="Rotter">Jerome I. 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Sisodiya</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-237182" status="INCOMING"> <orgName>Department of Clinical and Experimental Epilepsy</orgName> <desc> <address> <addrLine>London, United Kingdom</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation active="#struct-300875" type="direct"></relation> </listRelation><tutelles><tutelle active="#struct-300875" type="direct"><org type="institution" xml:id="struct-300875" status="VALID"> <orgName>University College of London [London]</orgName> <desc> <address> <addrLine>Gower Street, London WC1E 6BT </addrLine> <country key="GB"></country> </address> <ref type="url">http://www.ucl.ac.uk/</ref> </desc></org></tutelle></tutelles></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Smith, Colin" sort="Smith, Colin" uniqKey="Smith C" first="Colin" last="Smith">Colin Smith</name></author><author><name sortKey="Smoller, Jordan W" sort="Smoller, Jordan W" uniqKey="Smoller J" first="Jordan W" last="Smoller">Jordan W. 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Steen</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-431775" status="INCOMING"> <orgName>NORMENT - KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, 5021 Bergen, Norway </orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Stott, David J" sort="Stott, David J" uniqKey="Stott D" first="David J" last="Stott">David J. 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Van Haren</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-431765" status="INCOMING"> <orgName>Brain Center Rudolf Magnus, Department of Psychiatry, University Medical Center Utrecht, Utrecht, 3584 CX, The Netherlands </orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Van Ent, Dennis" sort="Van Ent, Dennis" uniqKey="Van Ent D" first="Dennis" last="Van Ent">Dennis Van Ent</name></author><author><name sortKey="Van Tol, Marie Jose" sort="Van Tol, Marie Jose" uniqKey="Van Tol M" first="Marie-Jose" last="Van Tol">Marie-Jose Van Tol</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-140870" status="INCOMING"> <orgName>LUMC</orgName> <desc> <address> <country key="NL"></country> </address> </desc> <listRelation> <relation active="#struct-327845" type="direct"></relation> </listRelation><tutelles><tutelle active="#struct-327845" type="direct"><org type="institution" xml:id="struct-327845" status="INCOMING"> <orgName>LUMC</orgName> <desc> <address> <country key="FR"></country> </address> </desc></org></tutelle></tutelles></hal:affiliation><country>Pays-Bas</country></affiliation></author><author><name sortKey="Vardarajan, Badri N" sort="Vardarajan, Badri N" uniqKey="Vardarajan B" first="Badri N" last="Vardarajan">Badri N. 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Wardlaw</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-61277" status="VALID"> <orgName>University of Edinburgh</orgName> <desc> <address> <addrLine>Old College South Bridge Edinburgh EH8 9YL</addrLine> <country key="GB"></country> </address> <ref type="url">http://www.ed.ac.uk/home</ref> </desc></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Wassink, Thomas H" sort="Wassink, Thomas H" uniqKey="Wassink T" first="Thomas H" last="Wassink">Thomas H. Wassink</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128986" status="INCOMING"> <orgName>Department of Psychiatry</orgName> <desc> <address> <addrLine>Iowa City, Iowa 52242</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-331255" type="direct"></relation> </listRelation><tutelles><tutelle active="#struct-331255" type="direct"><org type="institution" xml:id="struct-331255" status="INCOMING"> <orgName>Carver College of Medicine</orgName> <desc> <address> <country key="FR"></country> </address> </desc></org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Weale, Michael E" sort="Weale, Michael E" uniqKey="Weale M" first="Michael E" last="Weale">Michael E. Weale</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-136410" status="INCOMING"> <orgName>Centre for Population Health Sciences</orgName> <desc> <address> <country key="GB"></country> </address> </desc> <listRelation> <relation active="#struct-333153" type="direct"></relation> </listRelation><tutelles><tutelle active="#struct-333153" type="direct"><org type="institution" xml:id="struct-333153" status="INCOMING"> <orgName>Centre for Population Health Sciences</orgName> <desc> <address> <country key="FR"></country> </address> </desc></org></tutelle></tutelles></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Weinberger, Wei" sort="Weinberger, Wei" uniqKey="Weinberger W" first="Wei" last="Weinberger">Wei Weinberger</name></author><author><name sortKey="Weiner, Wei" sort="Weiner, Wei" uniqKey="Weiner W" first="Wei" last="Weiner">Wei Weiner</name></author><author><name sortKey="Wen, Wei" sort="Wen, Wei" uniqKey="Wen W" first="Wei" last="Wen">Wei Wen</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-220818" status="INCOMING"> <orgName>Department of Physics</orgName> <desc> <address> <country key="HK"></country> </address> </desc> <listRelation> <relation active="#struct-353702" type="direct"></relation> </listRelation><tutelles><tutelle active="#struct-353702" type="direct"><org type="institution" xml:id="struct-353702" status="INCOMING"> <orgName>Hong-Kong University of Science and Technology</orgName> <desc> <address> <country key="FR"></country> </address> </desc></org></tutelle></tutelles></hal:affiliation><country>Hong Kong</country></affiliation></author><author><name sortKey="Westman, Eric" sort="Westman, Eric" uniqKey="Westman E" first="Eric" last="Westman">Eric Westman</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-431839" status="INCOMING"> <orgName>Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm SE-141 83, Sweden </orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="White, Tonya" sort="White, Tonya" uniqKey="White T" first="Tonya" last="White">Tonya White</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-115724" status="INCOMING"> <orgName>Research Laboratory for Archaeology & the History of Art</orgName> <desc> <address> <addrLine>oxford</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation active="#struct-328015" type="direct"></relation> </listRelation><tutelles><tutelle active="#struct-328015" type="direct"><org type="institution" xml:id="struct-328015" status="INCOMING"> <orgName>Research Laboratory for Archaeology & the History of Art</orgName> <desc> <address> <country key="FR"></country> </address> </desc></org></tutelle></tutelles></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Wong, Tien Y" sort="Wong, Tien Y" uniqKey="Wong T" first="Tien Y" last="Wong">Tien Y. Wong</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-432665" status="INCOMING"> <orgName>Singapore Eye Research Institute, Singapore National Eye Centre</orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Wright, Clinton B" sort="Wright, Clinton B" uniqKey="Wright C" first="Clinton B" last="Wright">Clinton B. Wright</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-16444" status="INCOMING"> <orgName>School of Life Sciences</orgName> <desc> <address> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-251827" type="direct"></relation> </listRelation><tutelles><tutelle active="#struct-251827" type="direct"><org type="institution" xml:id="struct-251827" status="VALID"> <orgName>Arizona State University [Tempe]</orgName> <orgName type="acronym">ASU</orgName> <desc> <address> <addrLine>325 E Apache Blvd, Tempe, AZ 85281, États-Unis</addrLine> <country key="US"></country> </address> <ref type="url">http://www.asu.edu/</ref> </desc></org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Zielke, H Ronald" sort="Zielke, H Ronald" uniqKey="Zielke H" first="H Ronald" last="Zielke">H Ronald Zielke</name></author><author><name sortKey="Zonderman, Alan B" sort="Zonderman, Alan B" uniqKey="Zonderman A" first="Alan B" last="Zonderman">Alan B. Zonderman</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-431840" status="INCOMING"> <orgName>Behavioral Epidemiology Section, National Institute on Aging Intramural Research Program, Baltimore, Maryland 20892, USA </orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Deary, Ian J" sort="Deary, Ian J" uniqKey="Deary I" first="Ian J" last="Deary">Ian J. Deary</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-431805" status="INCOMING"> <orgName>Centre for Cognitive Ageing and Cognitive Epidemiology, Psychology, University of Edinburgh, Edinburgh EH8 9JZ, UK </orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Decarli, Charles" sort="Decarli, Charles" uniqKey="Decarli C" first="Charles" last="Decarli">Charles Decarli</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-423113" status="INCOMING"> <orgName>Department of Neurology and Center for Neuroscience, University of California at Davis, Sacramento</orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Schmidt, Helena" sort="Schmidt, Helena" uniqKey="Schmidt H" first="Helena" last="Schmidt">Helena Schmidt</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-456907" status="VALID"> <orgName>Dpt of Pharmacology and Personalised Medicine [Maastricht]</orgName> <desc> <address> <addrLine>PO Box 616 - 6200 MD Maastricht</addrLine> <country key="NL"></country> </address> </desc> <listRelation> <relation active="#struct-83832" type="direct"></relation> <relation active="#struct-456906" type="direct"></relation> </listRelation><tutelles><tutelle active="#struct-83832" type="direct"><org type="institution" xml:id="struct-83832" status="VALID"> <orgName>Maastricht University [Maastricht]</orgName> <desc> <address> <addrLine>Universiteitssingel 40;6200 MD Maastricht</addrLine> <country key="NL"></country> </address> <ref type="url">http://www.maastrichtuniversity.nl/</ref> </desc></org></tutelle><tutelle active="#struct-456906" type="direct"><org type="institution" xml:id="struct-456906" status="INCOMING"> <orgName>School for Cardiovascular Diseases in Maastricht</orgName> <orgName type="acronym">CARIM</orgName> <desc> <address> <addrLine>Maastricht University - Faculty of Health, Medicine & Life Science - PO Box 616 - 6200 MD Maastricht</addrLine> <country key="NL"></country> </address> </desc></org></tutelle></tutelles></hal:affiliation><country>Pays-Bas</country></affiliation></author><author><name sortKey="Martin, Nicholas G" sort="Martin, Nicholas G" uniqKey="Martin N" first="Nicholas G" last="Martin">Nicholas G. Martin</name></author><author><name sortKey="De Craen, Anton J M" sort="De Craen, Anton J M" uniqKey="De Craen A" first="Anton J M" last="De Craen">Anton J M. De Craen</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-138291" status="INCOMING"> <orgName>Department of neurology</orgName> <desc> <address> <addrLine>P.O. Box 9600, Albinusdreef 2, 2300 RC Leiden</addrLine> <country key="NL"></country> </address> </desc> <listRelation> <relation active="#struct-329273" type="direct"></relation> </listRelation><tutelles><tutelle active="#struct-329273" type="direct"><org type="institution" xml:id="struct-329273" status="INCOMING"> <orgName>Leiden University Medical Center</orgName> <desc> <address> <country key="FR"></country> </address> </desc></org></tutelle></tutelles></hal:affiliation><country>Pays-Bas</country></affiliation></author><author><name sortKey="Wright, Margaret J" sort="Wright, Margaret J" uniqKey="Wright M" first="Margaret J" last="Wright">Margaret J. Wright</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-136087" status="VALID"> <orgName>University of Missouri [Columbia]</orgName> <desc> <address> <addrLine>Columbia, MO 65211</addrLine> <country key="US"></country> </address> <ref type="url">http://missouri.edu/</ref> </desc></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Launer, Lenore J" sort="Launer, Lenore J" uniqKey="Launer L" first="Lenore J" last="Launer">Lenore J. Launer</name></author><author><name sortKey="Schumann, Gunter" sort="Schumann, Gunter" uniqKey="Schumann G" first="Gunter" last="Schumann">Gunter Schumann</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-57127" status="INCOMING"> <orgName>Göttingen Zentrum Geowissenschaften</orgName> <desc> <address> <addrLine>Abteilung Geobiologie, Goldschmidtstrasse 3, D-37077 Göttingen</addrLine> <country key="DE"></country> </address> </desc> <listRelation> <relation active="#struct-300741" type="direct"></relation> </listRelation><tutelles><tutelle active="#struct-300741" type="direct"><org type="institution" xml:id="struct-300741" status="VALID"> <orgName>Universität Göttingen</orgName> <date type="start">1737</date> <desc> <address> <addrLine>Wilhelmsplatz 1, 37073 Göttingen</addrLine> <country key="DE"></country> </address> <ref type="url">http://www.uni-goettingen.de/</ref> </desc></org></tutelle></tutelles></hal:affiliation><country>Allemagne</country><placeName><settlement type="city">Göttingen</settlement><region type="land" nuts="1">Basse-Saxe</region></placeName><orgName type="university">Université de Göttingen</orgName></affiliation></author><author><name sortKey="Fornage, Myriam" sort="Fornage, Myriam" uniqKey="Fornage M" first="Myriam" last="Fornage">Myriam Fornage</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-420496" status="INCOMING"> <orgName>Brown Foundation Institute of Molecular Medicine, The University of Texas Health Sciences Center at Houston, Houston, Texas, USA.</orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Franke, Barbara" sort="Franke, Barbara" uniqKey="Franke B" first="Barbara" last="Franke">Barbara Franke</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-173320" status="INCOMING"> <orgName>Donders Center for Cognitive Neuroimaging</orgName> <desc> <address> <country key="NL"></country> </address> </desc> <listRelation> <relation active="#struct-343852" type="direct"></relation> </listRelation><tutelles><tutelle active="#struct-343852" type="direct"><org type="institution" xml:id="struct-343852" status="INCOMING"> <orgName>Donders Center for Cognitive Neuroimaging</orgName> <desc> <address> <country key="FR"></country> </address> </desc></org></tutelle></tutelles></hal:affiliation><country>Pays-Bas</country></affiliation></author><author><name sortKey="Debette, Stephanie" sort="Debette, Stephanie" uniqKey="Debette S" first="Stéphanie" last="Debette">Stéphanie Debette</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-55677" status="VALID"> <orgName>Epidémiologie et Biostatistique [Bordeaux]</orgName> <desc> <address> <addrLine>146, rue Léo-Saignat 33076 Bordeaux</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation active="#struct-91134" type="direct"></relation> <relation active="#struct-302259" type="direct"></relation> <relation name="U897" active="#struct-303623" type="direct"></relation> </listRelation><tutelles><tutelle active="#struct-91134" type="direct"><org type="institution" xml:id="struct-91134" status="OLD"> <orgName>Université Bordeaux Segalen - Bordeaux 2</orgName> <desc> <address> <addrLine>146 rue Léo Saignat - 33076 Bordeaux cedex</addrLine> <country key="FR"></country> </address> <ref type="url">http://www.univ-bordeauxsegalen.fr/</ref> </desc></org></tutelle><tutelle active="#struct-302259" type="direct"><org type="institution" xml:id="struct-302259" status="VALID"> <orgName>Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)</orgName> <desc> <address> <country key="FR"></country> </address> </desc></org></tutelle><tutelle name="U897" active="#struct-303623" type="direct"><org type="institution" xml:id="struct-303623" status="VALID"> <idno type="IdRef">026388278</idno> <orgName>Institut National de la Santé et de la Recherche Médicale</orgName> <orgName type="acronym">INSERM</orgName> <desc> <address> <addrLine>101, rue de Tolbiac, 75013 Paris </addrLine> <country key="FR"></country> </address> <ref type="url">http://www.inserm.fr</ref> </desc></org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Medland, Sarah E" sort="Medland, Sarah E" uniqKey="Medland S" first="Sarah E" last="Medland">Sarah E. Medland</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-420528" status="INCOMING"> <orgName>Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Queensland, Australia</orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Ikram, M Arfan" sort="Ikram, M Arfan" uniqKey="Ikram M" first="M Arfan" last="Ikram">M Arfan Ikram</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-420494" status="INCOMING"> <orgName>Department of Radiology, Erasmus Medical Center University Medical Center, Rotterdam, The Netherlands</orgName> <desc> <address> <country key="FR"></country> </address> </desc></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Thompson, Paul M" sort="Thompson, Paul M" uniqKey="Thompson P" first="Paul M" last="Thompson">Paul M. Thompson</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-464414" status="INCOMING"> <orgName>Imaging Genetics Center, Mark & Mary Stevens Neuroimaging & Informatics Institute, University of Southern California, Marina del Rey, CA, USA</orgName> <desc> <address> <country key="US"></country> </address> </desc></hal:affiliation><country>États-Unis</country></affiliation></author></analytic><idno type="DOI">10.1038/nn.4398</idno><series><title level="j">Nature Neuroscience</title><idno type="ISSN">1097-6256</idno><imprint><date type="datePub">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="mix" xml:lang="en"><term> Development of the nervous system</term><term> Genome-wide association studies</term><term> Image processing</term><term>Brain</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Intracranial volume reflects the maximally attained brain size during development, and remains stable with loss of tissue in late life. It is highly heritable, but the underlying genes remain largely undetermined. In a genome-wide association study of 32,438 adults, we discovered five previously unknown loci for intracranial volume and confirmed two known signals. Four of the loci were also associated with adult human stature, but these remained associated with intracranial volume after adjusting for height. We found a high genetic correlation with child head circumference (ρgenetic = 0.748), which indicates a similar genetic background and allowed us to identify four additional loci through meta-analysis (Ncombined = 37,345). Variants for intracranial volume were also related to childhood and adult cognitive function, and Parkinson's disease, and were enriched near genes involved in growth pathways, including PI3K-AKT signaling. These findings identify the biological underpinnings of intracranial volume and their link to physiological and pathological traits.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Canada</li><li>Danemark</li><li>Finlande</li><li>France</li><li>Hong Kong</li><li>Iran</li><li>Irlande (pays)</li><li>Italie</li><li>Japon</li><li>Norvège</li><li>Pays-Bas</li><li>Portugal</li><li>Royaume-Uni</li><li>République populaire de Chine</li><li>Suisse</li><li>Suède</li><li>États-Unis</li></country><region><li>Alsace (région administrative)</li><li>Aquitaine</li><li>Basse-Saxe</li><li>East Middle Sweden</li><li>Grand Est</li><li>Lorraine (région)</li><li>Nouvelle-Aquitaine</li><li>Pennsylvanie</li><li>Québec</li><li>Svealand</li><li>Écosse</li></region><settlement><li>Bordeaux</li><li>Glasgow</li><li>Göttingen</li><li>Metz</li><li>Montréal</li><li>Nancy</li><li>Pittsburgh</li><li>Strasbourg</li><li>Uppsala</li></settlement><orgName><li>Université McGill</li><li>Université Strasbourg 1</li><li>Université d'Uppsala</li><li>Université de Bordeaux</li><li>Université de Glasgow</li><li>Université de Göttingen</li><li>Université de Lorraine</li><li>Université de Pittsburgh</li><li>Université de Strasbourg</li></orgName></list><tree><noCountry><name sortKey="Aggarwal, Neelum T" sort="Aggarwal, Neelum T" uniqKey="Aggarwal N" first="Neelum T" last="Aggarwal">Neelum T. Aggarwal</name><name sortKey="Andersson, Micael" sort="Andersson, Micael" uniqKey="Andersson M" first="Micael" last="Andersson">Micael Andersson</name><name sortKey="Andreassen, Andreas" sort="Andreassen, Andreas" uniqKey="Andreassen A" first="Andreas" last="Andreassen">Andreas Andreassen</name><name sortKey="Becker, Diane M" sort="Becker, Diane M" uniqKey="Becker D" first="Diane M" last="Becker">Diane M. Becker</name><name sortKey="Bennett, David A" sort="Bennett, David A" uniqKey="Bennett D" first="David A" last="Bennett">David A. Bennett</name><name sortKey="Bernard, Bernard" sort="Bernard, Bernard" uniqKey="Bernard B" first="Bernard" last="Bernard">Bernard Bernard</name><name sortKey="Blanken, Laura" sort="Blanken, Laura" uniqKey="Blanken L" first="Laura" last="Blanken">Laura Blanken</name><name sortKey="Braber, Anouk Den" sort="Braber, Anouk Den" uniqKey="Braber A" first="Anouk Den" last="Braber">Anouk Den Braber</name><name sortKey="Buckner, Randy L" sort="Buckner, Randy L" uniqKey="Buckner R" first="Randy L" last="Buckner">Randy L. Buckner</name><name sortKey="Chen, Christophe" sort="Chen, Christophe" uniqKey="Chen C" first="Christophe" last="Chen">Christophe Chen</name><name sortKey="Cheng, Ching Yu" sort="Cheng, Ching Yu" uniqKey="Cheng C" first="Ching-Yu" last="Cheng">Ching-Yu Cheng</name><name sortKey="Ching, Christophe" sort="Ching, Christophe" uniqKey="Ching C" first="Christophe" last="Ching">Christophe Ching</name><name sortKey="Djurovic, Srdjan" sort="Djurovic, Srdjan" uniqKey="Djurovic S" first="Srdjan" last="Djurovic">Srdjan Djurovic</name><name sortKey="Evans, Denis A" sort="Evans, Denis A" uniqKey="Evans D" first="Denis A" last="Evans">Denis A. Evans</name><name sortKey="Fernandez, Guillen" sort="Fernandez, Guillen" uniqKey="Fernandez G" first="Guillén" last="Fernández">Guillén Fernández</name><name sortKey="Ferrucci, Luigi" sort="Ferrucci, Luigi" uniqKey="Ferrucci L" first="Luigi" last="Ferrucci">Luigi Ferrucci</name><name sortKey="Filippi, Irina" sort="Filippi, Irina" uniqKey="Filippi I" first="Irina" last="Filippi">Irina Filippi</name><name sortKey="Ford, Ian" sort="Ford, Ian" uniqKey="Ford I" first="Ian" last="Ford">Ian Ford</name><name sortKey="Goldman, Aaron L" sort="Goldman, Aaron L" uniqKey="Goldman A" first="Aaron L" last="Goldman">Aaron L. Goldman</name><name sortKey="Greven, Corina U" sort="Greven, Corina U" uniqKey="Greven C" first="Corina U" last="Greven">Corina U. Greven</name><name sortKey="Griswold, Michael E" sort="Griswold, Michael E" uniqKey="Griswold M" first="Michael E" last="Griswold">Michael E. Griswold</name><name sortKey="Gruber, Oliver" sort="Gruber, Oliver" uniqKey="Gruber O" first="Oliver" last="Gruber">Oliver Gruber</name><name sortKey="Heinz, Andreas" sort="Heinz, Andreas" uniqKey="Heinz A" first="Andreas" last="Heinz">Andreas Heinz</name><name sortKey="Hernandez, Dena G" sort="Hernandez, Dena G" uniqKey="Hernandez D" first="Dena G" last="Hernandez">Dena G. Hernandez</name><name sortKey="Hernandez, Maria C Valdes" sort="Hernandez, Maria C Valdes" uniqKey="Hernandez M" first="Maria C Valdés" last="Hernández">Maria C Valdés Hernández</name><name sortKey="Ho, David" sort="Ho, David" uniqKey="Ho D" first="David" last="Ho">David Ho</name><name sortKey="Hoffmann, Wolfgang" sort="Hoffmann, Wolfgang" uniqKey="Hoffmann W" first="Wolfgang" last="Hoffmann">Wolfgang Hoffmann</name><name sortKey="Jenkinson, Mark" sort="Jenkinson, Mark" uniqKey="Jenkinson M" first="Mark" last="Jenkinson">Mark Jenkinson</name><name sortKey="Jr, Clifford R Jack" sort="Jr, Clifford R Jack" uniqKey="Jr C" first="Clifford R Jack" last="Jr">Clifford R Jack Jr</name><name sortKey="Jr, W T Longstreth" sort="Jr, W T Longstreth" uniqKey="Jr W" first="W T Longstreth" last="Jr">W T Longstreth Jr</name><name sortKey="Kahn, Rene S" sort="Kahn, Rene S" uniqKey="Kahn R" first="René S" last="Kahn">René S. Kahn</name><name sortKey="Klein, Marieke" sort="Klein, Marieke" uniqKey="Klein M" first="Marieke" last="Klein">Marieke Klein</name><name sortKey="Launer, Lenore J" sort="Launer, Lenore J" uniqKey="Launer L" first="Lenore J" last="Launer">Lenore J. Launer</name><name sortKey="Lee, Sven" sort="Lee, Sven" uniqKey="Lee S" first="Sven" last="Lee">Sven Lee</name><name sortKey="Liao, Li" sort="Liao, Li" uniqKey="Liao L" first="Li" last="Liao">Li Liao</name><name sortKey="Liu, Xinmin" sort="Liu, Xinmin" uniqKey="Liu X" first="Xinmin" last="Liu">Xinmin Liu</name><name sortKey="Loohuis, Loes M Olde" sort="Loohuis, Loes M Olde" uniqKey="Loohuis L" first="Loes M Olde" last="Loohuis">Loes M Olde Loohuis</name><name sortKey="Lopez, Lorna M" sort="Lopez, Lorna M" uniqKey="Lopez L" first="Lorna M" last="Lopez">Lorna M. Lopez</name><name sortKey="Maniega, Susana Mu Oz" sort="Maniega, Susana Mu Oz" uniqKey="Maniega S" first="Susana Mu Oz" last="Maniega">Susana Mu Oz Maniega</name><name sortKey="Marquand, Mar" sort="Marquand, Mar" uniqKey="Marquand M" first="Mar" last="Marquand">Mar Marquand</name><name sortKey="Martin, Jean Luc" sort="Martin, Jean Luc" uniqKey="Martin J" first="Jean-Luc" last="Martin">Jean-Luc Martin</name><name sortKey="Martin, Mar" sort="Martin, Mar" uniqKey="Martin M" first="Mar" last="Martin">Mar Martin</name><name sortKey="Martin, Martina" sort="Martin, Martina" uniqKey="Martin M" first="Martina" last="Martin">Martina Martin</name><name sortKey="Martin, Nicholas G" sort="Martin, Nicholas G" uniqKey="Martin N" first="Nicholas G" last="Martin">Nicholas G. Martin</name><name sortKey="Martin, Oliver" sort="Martin, Oliver" uniqKey="Martin O" first="Oliver" last="Martin">Oliver Martin</name><name sortKey="Mcmahon, Francis J" sort="Mcmahon, Francis J" uniqKey="Mcmahon F" first="Francis J" last="Mcmahon">Francis J. Mcmahon</name><name sortKey="Mcwhirter, Rebekah" sort="Mcwhirter, Rebekah" uniqKey="Mcwhirter R" first="Rebekah" last="Mcwhirter">Rebekah Mcwhirter</name><name sortKey="Mirza Schreiber, Nazanin" sort="Mirza Schreiber, Nazanin" uniqKey="Mirza Schreiber N" first="Nazanin" last="Mirza-Schreiber">Nazanin Mirza-Schreiber</name><name sortKey="Oosterlaan, Jaap" sort="Oosterlaan, Jaap" uniqKey="Oosterlaan J" first="Jaap" last="Oosterlaan">Jaap Oosterlaan</name><name sortKey="Pappa, Irene" sort="Pappa, Irene" uniqKey="Pappa I" first="Irene" last="Pappa">Irene Pappa</name><name sortKey="Pike, G Bruce" sort="Pike, G Bruce" uniqKey="Pike G" first="G Bruce" last="Pike">G Bruce Pike</name><name sortKey="Pirpamer, Lukas" sort="Pirpamer, Lukas" uniqKey="Pirpamer L" first="Lukas" last="Pirpamer">Lukas Pirpamer</name><name sortKey="Pol, Hilleke E Hulshoff" sort="Pol, Hilleke E Hulshoff" uniqKey="Pol H" first="Hilleke E Hulshoff" last="Pol">Hilleke E Hulshoff Pol</name><name sortKey="Pudas, Sara" sort="Pudas, Sara" uniqKey="Pudas S" first="Sara" last="Pudas">Sara Pudas</name><name sortKey="Richards, Jennifer S" sort="Richards, Jennifer S" uniqKey="Richards J" first="Jennifer S" last="Richards">Jennifer S. Richards</name><name sortKey="Rundek, Tatjana" sort="Rundek, Tatjana" uniqKey="Rundek T" first="Tatjana" last="Rundek">Tatjana Rundek</name><name sortKey="Sacco, Ralph L" sort="Sacco, Ralph L" uniqKey="Sacco R" first="Ralph L" last="Sacco">Ralph L. Sacco</name><name sortKey="Schmidt, Reinhold" sort="Schmidt, Reinhold" uniqKey="Schmidt R" first="Reinhold" last="Schmidt">Reinhold Schmidt</name><name sortKey="Shin, Jean" sort="Shin, Jean" uniqKey="Shin J" first="Jean" last="Shin">Jean Shin</name><name sortKey="Shumskaya, Elena" sort="Shumskaya, Elena" uniqKey="Shumskaya E" first="Elena" last="Shumskaya">Elena Shumskaya</name><name sortKey="Simmons, Andy" sort="Simmons, Andy" uniqKey="Simmons A" first="Andy" last="Simmons">Andy Simmons</name><name sortKey="Smith, Albert" sort="Smith, Albert" uniqKey="Smith A" first="Albert" last="Smith">Albert Smith</name><name sortKey="Smith, Colin" sort="Smith, Colin" uniqKey="Smith C" first="Colin" last="Smith">Colin Smith</name><name sortKey="Thomson, Russell" sort="Thomson, Russell" uniqKey="Thomson R" first="Russell" last="Thomson">Russell Thomson</name><name sortKey="Tordesillas Gutierrez, Diana" sort="Tordesillas Gutierrez, Diana" uniqKey="Tordesillas Gutierrez D" first="Diana" last="Tordesillas-Gutierrez">Diana Tordesillas-Gutierrez</name><name sortKey="Troncoso, Juan" sort="Troncoso, Juan" uniqKey="Troncoso J" first="Juan" last="Troncoso">Juan Troncoso</name><name sortKey="Vaidya, Dhananjay" sort="Vaidya, Dhananjay" uniqKey="Vaidya D" first="Dhananjay" last="Vaidya">Dhananjay Vaidya</name><name sortKey="Van Ent, Dennis" sort="Van Ent, Dennis" uniqKey="Van Ent D" first="Dennis" last="Van Ent">Dennis Van Ent</name><name sortKey="Van Erp, Theo G M" sort="Van Erp, Theo G M" uniqKey="Van Erp T" first="Theo G M" last="Van Erp">Theo G M. Van Erp</name><name sortKey="Vardarajan, Badri N" sort="Vardarajan, Badri N" uniqKey="Vardarajan B" first="Badri N" last="Vardarajan">Badri N. Vardarajan</name><name sortKey="Weinberger, Wei" sort="Weinberger, Wei" uniqKey="Weinberger W" first="Wei" last="Weinberger">Wei Weinberger</name><name sortKey="Weiner, Wei" sort="Weiner, Wei" uniqKey="Weiner W" first="Wei" last="Weiner">Wei Weiner</name><name sortKey="Wolf, Christiane" sort="Wolf, Christiane" uniqKey="Wolf C" first="Christiane" last="Wolf">Christiane Wolf</name><name sortKey="Wolfers, Thomas W" sort="Wolfers, Thomas W" uniqKey="Wolfers T" first="Thomas W" last="Wolfers">Thomas W. Wolfers</name><name sortKey="Xu, Bing" sort="Xu, Bing" uniqKey="Xu B" first="Bing" last="Xu">Bing Xu</name><name sortKey="Yang, Jingyun" sort="Yang, Jingyun" uniqKey="Yang J" first="Jingyun" last="Yang">Jingyun Yang</name><name sortKey="Zielke, H Ronald" sort="Zielke, H Ronald" uniqKey="Zielke H" first="H Ronald" last="Zielke">H Ronald Zielke</name></noCountry><country name="France"><region name="Grand Est"><name sortKey="Adams, Hieab H H" sort="Adams, Hieab H H" uniqKey="Adams H" first="Hieab H H" last="Adams">Hieab H H. Adams</name></region><name sortKey="Abramovic, Lucija" sort="Abramovic, Lucija" uniqKey="Abramovic L" first="Lucija" last="Abramovic">Lucija Abramovic</name><name sortKey="Alhusaini, Saud" sort="Alhusaini, Saud" uniqKey="Alhusaini S" first="Saud" last="Alhusaini">Saud Alhusaini</name><name sortKey="Amin, Najaf" sort="Amin, Najaf" uniqKey="Amin N" first="Najaf" last="Amin">Najaf Amin</name><name sortKey="Amouyel, Philippe" sort="Amouyel, Philippe" uniqKey="Amouyel P" first="Philippe" last="Amouyel">Philippe Amouyel</name><name sortKey="Arfanakis, Konstantinos" sort="Arfanakis, Konstantinos" uniqKey="Arfanakis K" first="Konstantinos" last="Arfanakis">Konstantinos Arfanakis</name><name sortKey="Aribisala, Benjamin S" sort="Aribisala, Benjamin S" uniqKey="Aribisala B" first="Benjamin S" last="Aribisala">Benjamin S. Aribisala</name><name sortKey="Athanasiu, Lavinia" sort="Athanasiu, Lavinia" uniqKey="Athanasiu L" first="Lavinia" last="Athanasiu">Lavinia Athanasiu</name><name sortKey="Barral, Sandra" sort="Barral, Sandra" uniqKey="Barral S" first="Sandra" last="Barral">Sandra Barral</name><name sortKey="Bis, Joshua C" sort="Bis, Joshua C" uniqKey="Bis J" first="Joshua C" last="Bis">Joshua C. Bis</name><name sortKey="Blangero, John B" sort="Blangero, John B" uniqKey="Blangero J" first="John B" last="Blangero">John B. Blangero</name><name sortKey="Bohlken, Mar" sort="Bohlken, Mar" uniqKey="Bohlken M" first="Mar" last="Bohlken">Mar Bohlken</name><name sortKey="Boks, Mar" sort="Boks, Mar" uniqKey="Boks M" first="Mar" last="Boks">Mar Boks</name><name sortKey="Bralten, Janita" sort="Bralten, Janita" uniqKey="Bralten J" first="Janita" last="Bralten">Janita Bralten</name><name sortKey="Bulayeva, Kazima B" sort="Bulayeva, Kazima B" uniqKey="Bulayeva K" first="Kazima B" last="Bulayeva">Kazima B. Bulayeva</name><name sortKey="Calhoun, Vince D" sort="Calhoun, Vince D" uniqKey="Calhoun V" first="Vince D" last="Calhoun">Vince D. Calhoun</name><name sortKey="Chauhan, Ganesh" sort="Chauhan, Ganesh" uniqKey="Chauhan G" first="Ganesh" last="Chauhan">Ganesh Chauhan</name><name sortKey="Chouraki, Vincent" sort="Chouraki, Vincent" uniqKey="Chouraki V" first="Vincent" last="Chouraki">Vincent Chouraki</name><name sortKey="Crespo Facorro, Benedicto" sort="Crespo Facorro, Benedicto" uniqKey="Crespo Facorro B" first="Benedicto" last="Crespo-Facorro">Benedicto Crespo-Facorro</name><name sortKey="Cuellar Partida, Gabriel" sort="Cuellar Partida, Gabriel" uniqKey="Cuellar Partida G" first="Gabriel" last="Cuellar-Partida">Gabriel Cuellar-Partida</name><name sortKey="De Jager, Philip L" sort="De Jager, Philip L" uniqKey="De Jager P" first="Philip L" last="De Jager">Philip L. De Jager</name><name sortKey="Deary, Ian J" sort="Deary, Ian J" uniqKey="Deary I" first="Ian J" last="Deary">Ian J. Deary</name><name sortKey="Debette, Stephanie" sort="Debette, Stephanie" uniqKey="Debette S" first="Stéphanie" last="Debette">Stéphanie Debette</name><name sortKey="Decarli, Charles" sort="Decarli, Charles" uniqKey="Decarli C" first="Charles" last="Decarli">Charles Decarli</name><name sortKey="Delanty, Norman" sort="Delanty, Norman" uniqKey="Delanty N" first="Norman" last="Delanty">Norman Delanty</name><name sortKey="Depondt, Chantal" sort="Depondt, Chantal" uniqKey="Depondt C" first="Chantal" last="Depondt">Chantal Depondt</name><name sortKey="Desrivieres, Sylvane" sort="Desrivieres, Sylvane" uniqKey="Desrivieres S" first="Sylvane" last="Desrivières">Sylvane Desrivières</name><name sortKey="Dillman, Allissa" sort="Dillman, Allissa" uniqKey="Dillman A" first="Allissa" last="Dillman">Allissa Dillman</name><name sortKey="Duggirala, Ravi" sort="Duggirala, Ravi" uniqKey="Duggirala R" first="Ravi" last="Duggirala">Ravi Duggirala</name><name sortKey="Dyer, Thomas" sort="Dyer, Thomas" uniqKey="Dyer T" first="Thomas" last="Dyer">Thomas Dyer</name><name sortKey="Ehrlich, Stefan" sort="Ehrlich, Stefan" uniqKey="Ehrlich S" first="Stefan" last="Ehrlich">Stefan Ehrlich</name><name sortKey="Espeseth, Thomas E" sort="Espeseth, Thomas E" uniqKey="Espeseth T" first="Thomas E" last="Espeseth">Thomas E. Espeseth</name><name sortKey="Fedko, Iryna O" sort="Fedko, Iryna O" uniqKey="Fedko I" first="Iryna O" last="Fedko">Iryna O. Fedko</name><name sortKey="Fleischman, Debra A" sort="Fleischman, Debra A" uniqKey="Fleischman D" first="Debra A" last="Fleischman">Debra A. Fleischman</name><name sortKey="Fornage, Myriam" sort="Fornage, Myriam" uniqKey="Fornage M" first="Myriam" last="Fornage">Myriam Fornage</name><name sortKey="Fox, Peter" sort="Fox, Peter" uniqKey="Fox P" first="Peter" last="Fox">Peter Fox</name><name sortKey="Francks, Clyde" sort="Francks, Clyde" uniqKey="Francks C" first="Clyde" last="Francks">Clyde Francks</name><name sortKey="Giddaluru, Sudheer" sort="Giddaluru, Sudheer" uniqKey="Giddaluru S" first="Sudheer" last="Giddaluru">Sudheer Giddaluru</name><name sortKey="Glahn, David C" sort="Glahn, David C" uniqKey="Glahn D" first="David C" last="Glahn">David C. Glahn</name><name sortKey="Guadalupe, Tulio" sort="Guadalupe, Tulio" uniqKey="Guadalupe T" first="Tulio" last="Guadalupe">Tulio Guadalupe</name><name sortKey="Gudnason, Vilmundur" sort="Gudnason, Vilmundur" uniqKey="Gudnason V" first="Vilmundur" last="Gudnason">Vilmundur Gudnason</name><name sortKey="Guelfi, Sebastian" sort="Guelfi, Sebastian" uniqKey="Guelfi S" first="Sebastian" last="Guelfi">Sebastian Guelfi</name><name sortKey="Hashimoto, Ryota" sort="Hashimoto, Ryota" uniqKey="Hashimoto R" first="Ryota" last="Hashimoto">Ryota Hashimoto</name><name sortKey="Haukvik, Unn K" sort="Haukvik, Unn K" uniqKey="Haukvik U" first="Unn K" last="Haukvik">Unn K. Haukvik</name><name sortKey="Hegenscheid, Katrin" sort="Hegenscheid, Katrin" uniqKey="Hegenscheid K" first="Katrin" last="Hegenscheid">Katrin Hegenscheid</name><name sortKey="Heslenfeld, Dirk J" sort="Heslenfeld, Dirk J" uniqKey="Heslenfeld D" first="Dirk J" last="Heslenfeld">Dirk J. Heslenfeld</name><name sortKey="Hibar, Derrek P" sort="Hibar, Derrek P" uniqKey="Hibar D" first="Derrek P" last="Hibar">Derrek P. Hibar</name><name sortKey="Hilal, Saima" sort="Hilal, Saima" uniqKey="Hilal S" first="Saima" last="Hilal">Saima Hilal</name><name sortKey="Ho, Beng Choon" sort="Ho, Beng Choon" uniqKey="Ho B" first="Beng-Choon" last="Ho">Beng-Choon Ho</name><name sortKey="Hosten, Norbert" sort="Hosten, Norbert" uniqKey="Hosten N" first="Norbert" last="Hosten">Norbert Hosten</name><name sortKey="Ikram, M Arfan" sort="Ikram, M Arfan" uniqKey="Ikram M" first="M Arfan" last="Ikram">M Arfan Ikram</name><name sortKey="Ikram, M Kamran" sort="Ikram, M Kamran" uniqKey="Ikram M" first="M Kamran" last="Ikram">M Kamran Ikram</name><name sortKey="Jahanshad, Neda" sort="Jahanshad, Neda" uniqKey="Jahanshad N" first="Neda" last="Jahanshad">Neda Jahanshad</name><name sortKey="Janowitz, Deborah" sort="Janowitz, Deborah" uniqKey="Janowitz D" first="Deborah" last="Janowitz">Deborah Janowitz</name><name sortKey="Jukema, J Wouter" sort="Jukema, J Wouter" uniqKey="Jukema J" first="J Wouter" last="Jukema">J Wouter Jukema</name><name sortKey="Kanai, Ryota" sort="Kanai, Ryota" uniqKey="Kanai R" first="Ryota" last="Kanai">Ryota Kanai</name><name sortKey="Kasperaviciute, Dalia" sort="Kasperaviciute, Dalia" uniqKey="Kasperaviciute D" first="Dalia" last="Kasperaviciute">Dalia Kasperaviciute</name><name sortKey="Kim, Sungeun" sort="Kim, Sungeun" uniqKey="Kim S" first="Sungeun" last="Kim">Sungeun Kim</name><name sortKey="Kloszewska, Iwona" sort="Kloszewska, Iwona" uniqKey="Kloszewska I" first="Iwona" last="Kloszewska">Iwona Kloszewska</name><name sortKey="Kochunov, Peter" sort="Kochunov, Peter" uniqKey="Kochunov P" first="Peter" last="Kochunov">Peter Kochunov</name><name sortKey="Kraemer, Bernd" sort="Kraemer, Bernd" uniqKey="Kraemer B" first="Bernd" last="Kraemer">Bernd Kraemer</name><name sortKey="Lawrie, Stephen M" sort="Lawrie, Stephen M" uniqKey="Lawrie S" first="Stephen M" last="Lawrie">Stephen M. Lawrie</name><name sortKey="Le Hellard, Stephanie" sort="Le Hellard, Stephanie" uniqKey="Le Hellard S" first="Stephanie" last="Le Hellard">Stephanie Le Hellard</name><name sortKey="Lemaitre, Herve" sort="Lemaitre, Herve" uniqKey="Lemaitre H" first="Hervé" last="Lemaître">Hervé Lemaître</name><name sortKey="Liewald, David C" sort="Liewald, David C" uniqKey="Liewald D" first="David C" last="Liewald">David C. Liewald</name><name sortKey="Longo, Dan L" sort="Longo, Dan L" uniqKey="Longo D" first="Dan L" last="Longo">Dan L. Longo</name><name sortKey="Lopez, Oscar L" sort="Lopez, Oscar L" uniqKey="Lopez O" first="Oscar L" last="Lopez">Oscar L. Lopez</name><name sortKey="Macare, Christine" sort="Macare, Christine" uniqKey="Macare C" first="Christine" last="Macare">Christine Macare</name><name sortKey="Mather, Karen A" sort="Mather, Karen A" uniqKey="Mather K" first="Karen A" last="Mather">Karen A. Mather</name><name sortKey="Mazoyer, Bernard" sort="Mazoyer, Bernard" uniqKey="Mazoyer B" first="Bernard" last="Mazoyer">Bernard Mazoyer</name><name sortKey="Mckay, David" sort="Mckay, David" uniqKey="Mckay D" first="David" last="Mckay">David Mckay</name><name sortKey="Medland, Sarah E" sort="Medland, Sarah E" uniqKey="Medland S" first="Sarah E" last="Medland">Sarah E. Medland</name><name sortKey="Meyer Lindenberg, Andreas" sort="Meyer Lindenberg, Andreas" uniqKey="Meyer Lindenberg A" first="Andreas" last="Meyer-Lindenberg">Andreas Meyer-Lindenberg</name><name sortKey="Milaneschi, Yuri" sort="Milaneschi, Yuri" uniqKey="Milaneschi Y" first="Yuri" last="Milaneschi">Yuri Milaneschi</name><name sortKey="Mohnke, Sebastian" sort="Mohnke, Sebastian" uniqKey="Mohnke S" first="Sebastian" last="Mohnke">Sebastian Mohnke</name><name sortKey="Morris, Derek W" sort="Morris, Derek W" uniqKey="Morris D" first="Derek W" last="Morris">Derek W. Morris</name><name sortKey="Mosley, Thomas H" sort="Mosley, Thomas H" uniqKey="Mosley T" first="Thomas H" last="Mosley">Thomas H. Mosley</name><name sortKey="Nalls, Michael A" sort="Nalls, Michael A" uniqKey="Nalls M" first="Michael A" last="Nalls">Michael A. Nalls</name><name sortKey="Nho, Kwangsik" sort="Nho, Kwangsik" uniqKey="Nho K" first="Kwangsik" last="Nho">Kwangsik Nho</name><name sortKey="Nyquist, Paul A" sort="Nyquist, Paul A" uniqKey="Nyquist P" first="Paul A" last="Nyquist">Paul A. Nyquist</name><name sortKey="Ohi, Kazutaka" sort="Ohi, Kazutaka" uniqKey="Ohi K" first="Kazutaka" last="Ohi">Kazutaka Ohi</name><name sortKey="Olvera, Rene L" sort="Olvera, Rene L" uniqKey="Olvera R" first="Rene L" last="Olvera">Rene L. Olvera</name><name sortKey="Pandolfo, Massimo" sort="Pandolfo, Massimo" uniqKey="Pandolfo M" first="Massimo" last="Pandolfo">Massimo Pandolfo</name><name sortKey="Potkin, Steven G" sort="Potkin, Steven G" uniqKey="Potkin S" first="Steven G" last="Potkin">Steven G. Potkin</name><name sortKey="Rajan, Kumar B" sort="Rajan, Kumar B" uniqKey="Rajan K" first="Kumar B" last="Rajan">Kumar B. Rajan</name><name sortKey="Renteria, Miguel E" sort="Renteria, Miguel E" uniqKey="Renteria M" first="Miguel E" last="Rentería">Miguel E. Rentería</name><name sortKey="Risacher, Shannon L" sort="Risacher, Shannon L" uniqKey="Risacher S" first="Shannon L" last="Risacher">Shannon L. Risacher</name><name sortKey="Roffman, Joshua L" sort="Roffman, Joshua L" uniqKey="Roffman J" first="Joshua L" last="Roffman">Joshua L. Roffman</name><name sortKey="Roiz Santia Ez, Robert" sort="Roiz Santia Ez, Robert" uniqKey="Roiz Santia Ez R" first="Robert" last="Roiz-Santia Ez">Robert Roiz-Santia Ez</name><name sortKey="Romanczuk Seiferth, Nina" sort="Romanczuk Seiferth, Nina" uniqKey="Romanczuk Seiferth N" first="Nina" last="Romanczuk-Seiferth">Nina Romanczuk-Seiferth</name><name sortKey="Rose, Emma" sort="Rose, Emma" uniqKey="Rose E" first="Emma" last="Rose">Emma Rose</name><name sortKey="Royle, Natalie A" sort="Royle, Natalie A" uniqKey="Royle N" first="Natalie A" last="Royle">Natalie A. Royle</name><name sortKey="Ryten, Mina" sort="Ryten, Mina" uniqKey="Ryten M" first="Mina" last="Ryten">Mina Ryten</name><name sortKey="S Mann, Philipp G" sort="S Mann, Philipp G" uniqKey="S Mann P" first="Philipp G" last="S Mann">Philipp G. S Mann</name><name sortKey="Satizabal, Claudia L" sort="Satizabal, Claudia L" uniqKey="Satizabal C" first="Claudia L" last="Satizabal">Claudia L. Satizabal</name><name sortKey="Saykin, Andrew" sort="Saykin, Andrew" uniqKey="Saykin A" first="Andrew" last="Saykin">Andrew Saykin</name><name sortKey="Schmaal, Li" sort="Schmaal, Li" uniqKey="Schmaal L" first="Li" last="Schmaal">Li Schmaal</name><name sortKey="Schork, Andrew" sort="Schork, Andrew" uniqKey="Schork A" first="Andrew" last="Schork">Andrew Schork</name><name sortKey="Sigurdsson, Sigurdur" sort="Sigurdsson, Sigurdur" uniqKey="Sigurdsson S" first="Sigurdur" last="Sigurdsson">Sigurdur Sigurdsson</name><name sortKey="Singleton, Andrew" sort="Singleton, Andrew" uniqKey="Singleton A" first="Andrew" last="Singleton">Andrew Singleton</name><name sortKey="Sprooten, Emma" sort="Sprooten, Emma" uniqKey="Sprooten E" first="Emma" last="Sprooten">Emma Sprooten</name><name sortKey="Srikanth, Velandai" sort="Srikanth, Velandai" uniqKey="Srikanth V" first="Velandai" last="Srikanth">Velandai Srikanth</name><name sortKey="Steen, Vidar M" sort="Steen, Vidar M" uniqKey="Steen V" first="Vidar M" last="Steen">Vidar M. Steen</name><name sortKey="Stein, Jason L" sort="Stein, Jason L" uniqKey="Stein J" first="Jason L" last="Stein">Jason L. Stein</name><name sortKey="Strike, Lachlan T" sort="Strike, Lachlan T" uniqKey="Strike L" first="Lachlan T" last="Strike">Lachlan T. Strike</name><name sortKey="Sussmann, Jessika E" sort="Sussmann, Jessika E" uniqKey="Sussmann J" first="Jessika E" last="Sussmann">Jessika E. Sussmann</name><name sortKey="Thalamuthu, Anbupalam" sort="Thalamuthu, Anbupalam" uniqKey="Thalamuthu A" first="Anbupalam" last="Thalamuthu">Anbupalam Thalamuthu</name><name sortKey="Toro, Robert" sort="Toro, Robert" uniqKey="Toro R" first="Robert" last="Toro">Robert Toro</name><name sortKey="Trabzuni, Daniah" sort="Trabzuni, Daniah" uniqKey="Trabzuni D" first="Daniah" last="Trabzuni">Daniah Trabzuni</name><name sortKey="Traynor, Bryan J" sort="Traynor, Bryan J" uniqKey="Traynor B" first="Bryan J" last="Traynor">Bryan J. Traynor</name><name sortKey="Trompet, Stella" sort="Trompet, Stella" uniqKey="Trompet S" first="Stella" last="Trompet">Stella Trompet</name><name sortKey="Tzourio, Christophe" sort="Tzourio, Christophe" uniqKey="Tzourio C" first="Christophe" last="Tzourio">Christophe Tzourio</name><name sortKey="Van Der Brug, Marcel" sort="Van Der Brug, Marcel" uniqKey="Van Der Brug M" first="Marcel" last="Van Der Brug">Marcel Van Der Brug</name><name sortKey="Van Der Grond, Jeroen" sort="Van Der Grond, Jeroen" uniqKey="Van Der Grond J" first="Jeroen" last="Van Der Grond">Jeroen Van Der Grond</name><name sortKey="Van Der Wee, Nic J A" sort="Van Der Wee, Nic J A" uniqKey="Van Der Wee N" first="Nic J A" last="Van Der Wee">Nic J A. Van Der Wee</name><name sortKey="Van Donkelaar, Marjolein M J" sort="Van Donkelaar, Marjolein M J" uniqKey="Van Donkelaar M" first="Marjolein M J" last="Van Donkelaar">Marjolein M J. Van Donkelaar</name><name sortKey="Van Haren, Neeltje E M" sort="Van Haren, Neeltje E M" uniqKey="Van Haren N" first="Neeltje E M" last="Van Haren">Neeltje E M. Van Haren</name><name sortKey="Veltman, Dick J" sort="Veltman, Dick J" uniqKey="Veltman D" first="Dick J" last="Veltman">Dick J. Veltman</name><name sortKey="Walton, Esther" sort="Walton, Esther" uniqKey="Walton E" first="Esther" last="Walton">Esther Walton</name><name sortKey="Westlye, Lars" sort="Westlye, Lars" uniqKey="Westlye L" first="Lars" last="Westlye">Lars Westlye</name><name sortKey="Westman, Eric" sort="Westman, Eric" uniqKey="Westman E" first="Eric" last="Westman">Eric Westman</name><name sortKey="Whelan, Christophe" sort="Whelan, Christophe" uniqKey="Whelan C" first="Christophe" last="Whelan">Christophe Whelan</name><name sortKey="Windham, Beverly G" sort="Windham, Beverly G" uniqKey="Windham B" first="Beverly G" last="Windham">Beverly G. 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